Efficacy of a single intra-articular injection of mesenchymal stem cells for knee osteoarthritis: a dose-focused meta-analysis of randomized controlled trials

Abstract Background Intra-articular injection of mesenchymal stem cells (MSCs) has emerged as a promising therapy for knee osteoarthritis (OA). However, uncertainty remains regarding the optimal cell dose for maximizing clinical benefit. This systematic review and meta-analysis aimed to evaluate the...

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Bibliographic Details

Main Authors:	Rizki Rahmadian, Zikril Ariliusra, Kevin Rizki Agung Kusuma, Hirowati Ali, Benni Raymond, Riki Meksiko
Format:	Artigo
Language:	Inglês
Published:	BMC 2025-08-01
Series:	Journal of Orthopaedic Surgery and Research
Subjects:	Intra-articular injection Mesenchymal stem cell Knee osteoarthritis
Online Access:	https://doi.org/10.1186/s13018-025-06190-4
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