An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis

N-Methyl-D-aspartate (NMDA) receptors (NMDARs) are among the most important excitatory neurotransmitter receptors in the human brain. Autoantibodies to the human NMDAR cause the most frequent form of autoimmune encephalitis involving autoantibody-mediated receptor cross-linking and subsequent intern...

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Principais autores:	Elsie Amedonu, Christoph Brenker, Sumanta Barman, Julian A. Schreiber, Sebastian Becker, Stefan Peischard, Nathalie Strutz-Seebohm, Christine Strippel, Andre Dik, Hans-Peter Hartung, Thomas Budde, Heinz Wiendl, Timo Strünker, Bernhard Wünsch, Norbert Goebels, Sven G. Meuth, Guiscard Seebohm, Nico Melzer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-03-01
coleção:	Frontiers in Neurology
Assuntos:	autoimmune encephalitis N-Methyl-D-aspartate receptors cross-linking endocytosis vesicular trafficking exocytosis
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fneur.2019.00178/full
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