Memory T-cell enriched haploidentical transplantation with NK cell addback results in promising long-term outcomes: a phase II trial

Abstract Background Relapse remains a challenge after transplantation in pediatric patients with hematological malignancies. Myeloablative regimens used for disease control are associated with acute and long-term adverse effects. We used a CD45RA-depleted haploidentical graft for adoptive transfer o...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Swati Naik, Ying Li, Aimee C. Talleur, Subodh Selukar, Emily Ashcraft, Cheng Cheng, Renee M. Madden, Ewelina Mamcarz, Amr Qudeimat, Akshay Sharma, Ashok Srinivasan, Ali Y. Suliman, Rebecca Epperly, Esther A. Obeng, M. Paulina Velasquez, Deanna Langfitt, Sarah Schell, Jean-Yves Métais, Paula Y. Arnold, Diego R. Hijano, Gabriela Maron, Thomas E. Merchant, Salem Akel, Wing Leung, Stephen Gottschalk, Brandon M. Triplett
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2024-06-01
סדרה:	Journal of Hematology & Oncology
נושאים:	Pediatric hematological malignancies Transplantation Haploidentical Memory T cell T-cell depletion CD45RA depletion
גישה מקוונת:	https://doi.org/10.1186/s13045-024-01567-0
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!