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Development of a liquid overlay-based three-dimensional cell culture panel for drug screening applications

Abstract 3D cell culture has emerged as a relevant and promising alternative model for improving the preclinical phase of pharmaceutical development. It mimics cell-cell and cell-matrix interactions, as well as drug penetration and toxicity responses. However, there are currently no standardized met...

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Principais autores: Marie Depresle, Pierre Daumar, Antoine Goisnard, Manon Roux, Corinne Aubel, Frédérique Penault-Llorca, Emmanuelle Mounetou, Mahchid Bamdad
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-12-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-025-26985-z
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