Development and validation of a stability-indicating RP-HPLC method for tizanidine hydrochloride using DOE

Background: Tizanidine hydrochloride (TIZ) is a centrally acting α2-adrenergic receptor agonist widely prescribed for managing spasticity. Given its therapeutic importance, a reliable, stability-indicating analytical method is crucial to ensure both the quality and regulatory compliance of Tizanidin...

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Hlavní autoři:	Prasad Gunjal, Janki Patel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Creative Pharma Assent 2025-06-01
Edice:	Journal of Applied Pharmaceutical Research
Témata:	tizanidine hydrochloride rp-hplc stability-indicating method design of experiments (doe) forced degradation analytical validation
On-line přístup:	https://japtronline.com/index.php/joapr/article/view/1057
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