MULTIPLEX PCR FOR DETECTION OF NPM1 W288CFS AND FLT3-ITD MUTATIONS IN ACUTE MYELOID LEUKEMIA PATIENTS IN AMAZONAS STATES, BRAZIL

Introduction: Acute Myeloid Leukemia (AML) is a hematological disease clonal characterized by proliferation neoplasm cells in the bone marrow and peripheral blood, in consequence genetic alterations at hematopoietic stem cells. Genetic variants, as FLT3-ITD and W288Cfs NPM1 are common in the AML, th...

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Auteurs principaux:	TCD Santos, LKG Sousa, GSP Braz, MOD Santos, MOD Nascimento, LA Cassa-Barbosa, LPS Mourão, AM Tarragô, GAV Silva
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2024-10-01
Collection:	Hematology, Transfusion and Cell Therapy
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S253113792400960X
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