Impact of a Formulation Containing Chaga Extract, Coenzyme Q10, and Alpha-Lipoic Acid on Mitochondrial Dysfunction and Oxidative Stress: NMR Metabolomic Insights into Cellular Energy

Objectives: The aim of this study was to evaluate the impact of a novel antioxidant formulation (RE:PAIR, RP-25) containing CoQ10, alpha-lipoic acid, and Chaga extract on mitochondrial dysfunction and oxidative stress. To explore the activity of the formulation on neuronal cells, we explored cell me...

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Autori principali:	Maria D’Elia, Carmen Marino, Rita Celano, Enza Napolitano, Chiara Colarusso, Rosalinda Sorrentino, Anna Maria D’Ursi, Luca Rastrelli
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-06-01
Serie:	Antioxidants
Soggetti:	coenzyme Q10 lipoic acid <i>Inonotus obliquus</i> SH-SY5Y cells UHPLC-HRMS/MS <sup>1</sup>H-NMR metabolomics
Accesso online:	https://www.mdpi.com/2076-3921/14/6/753
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