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Complementary Cell Lines for Protease Gene-Deleted Single-Cycle Adenovirus Vectors

To increase the safety of adenovirus vector (AdV)-based therapy without reducing its efficacy, a single-cycle adenovirus vector (SC-AdV) with a deletion in the protease gene (PS) was developed in order to be used as a substitute for the replication-competent adenovirus (RC-AdV). Since no infectious...

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Bibliografische gegevens
Hoofdauteurs: Seyyed Mehdy Elahi, Nazila Nazemi-Moghaddam, Claire Guilbault, Mélanie Simoneau, Rénald Gilbert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2023-02-01
Reeks:Cells
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Online toegang:https://www.mdpi.com/2073-4409/12/4/619
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