Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells

Abstract Background The metabolic reprogramming of mesenchymal stem/stromal cells (MSC) favoring glycolysis has recently emerged as a new approach to improve their immunotherapeutic abilities. This strategy is associated with greater lactate release, and interestingly, recent studies have proposed l...

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Principais autores:	Carolina Pradenas, Noymar Luque-Campos, Karina Oyarce, Rafael Contreras-Lopez, Felipe A. Bustamante-Barrientos, Andrés Bustos, Felipe Galvez-Jiron, María Jesús Araya, Catalina Asencio, Raúl Lagos, Yeimi Herrera-Luna, Daouda Abba Moussa, Charlotte Nicole Hill, Eliana Lara-Barba, Claudia Altamirano, Alexander Ortloff, Yessia Hidalgo-Fadic, Ana María Vega-Letter, María de los Ángeles García-Robles, Farida Djouad, Patricia Luz-Crawford, Roberto Elizondo-Vega
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2023-11-01
סדרה:	Stem Cell Research & Therapy
נושאים:	Mesenchymal stem/stromal cells Glycolytic metabolism Lactate dehydrogenase, lactate Immunosuppression Th1 and Th17 cells
גישה מקוונת:	https://doi.org/10.1186/s13287-023-03549-4
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