Generation of Hydrogen Peroxide and Downstream Protein Kinase D1 Signaling Is a Common Feature of Inducers of Pancreatic Acinar-to-Ductal Metaplasia

Pancreatic acinar-to-ductal metaplasia (ADM) is a reversible process that occurs after pancreatic injury, but becomes permanent and leads to pancreatic lesions in the presence of an oncogenic mutation in KRAS,. While inflammatory macrophage-secreted chemokines, growth factors that activate epidermal...

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Autors principals:	Heike R. Döppler, Geou-Yarh Liou, Peter Storz
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-01-01
Col·lecció:	Antioxidants
Matèries:	hydrogen peroxide oxidative stress ADM acinar-to-ductal metaplasia pancreas PKD
Accés en línia:	https://www.mdpi.com/2076-3921/11/1/137
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