Antiparkinsonian effects of the "Radiprodil and Tozadenant" combination in MPTP-treated marmosets.

Investigate a combination of two clinically tested drugs, the NR2B antagonist Radiprodil and the A2A antagonist Tozadenant in the MPTP-treated marmoset model of Parkinson's Disease (PD).In PD, there remains a need for the development of non-dopaminergic drugs to effectively treat the motor symptoms...

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Principais autores:	Anne Michel, Jean-Marie Nicolas, Sarah Rose, Michael Jackson, Peter Colman, Willy Briône, David Sciberras, Pierandrea Muglia, Dieter K Scheller, Martin Citron, Patrick Downey
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2017-01-01
סדרה:	PLoS ONE
גישה מקוונת:	http://europepmc.org/articles/PMC5576667?pdf=render
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