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Harmonization and qualification of intracellular cytokine staining to measure influenza-specific CD4+ T cell immunity within the FLUCOP consortium

Despite the knowledge that cell-mediated immunity (CMI) contributes to the reduction of severe influenza infection, transmission, and disease outcome, the correlates of protection for cell-mediated immunity remain still unclear. Therefore, measuring the magnitude and quality of influenza-specific T...

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Principais autores: Sarah Begue, Gwenn Waerlop, Bruno Salaun, Michel Janssens, Duncan Bellamy, Rebecca Jane Cox, Richard Davies, Elena Gianchecchi, Donata Medaglini, Emanuele Montomoli, Elena Pettini, Geert Leroux-Roels, Frédéric Clement, Anke Pagnon
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-10-01
Serier:Frontiers in Immunology
Fag:
cell-mediated immunity
FLUCOP
influenza vaccine
intracellular cytokine staining
polypositive T cells
standard operating procedure
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.982887/full
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