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Unveiling the potential role of natriuretic peptide receptor a isoforms in fine-tuning the cGMP production and tissue-specific function

Abstract Atrial natriuretic peptide (ANP) is a peptide hormone that regulates blood pressure and volume. ANP interacts with natriuretic peptide receptor-A (NPR-A) to lower the blood pressure through vasodilation, diuresis and natriuresis. Previously, we designed two human ANP analogues, one with exc...

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Principais autores: Wei Fong Ang, Dan Liao, Cho Yeow Koh, R. Manjunatha Kini
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2023-11-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-023-47710-8
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