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Automated cytometric gating with human-level performance using bivariate segmentation

Abstract Recent advances in cytometry have enabled high-throughput data collection with multiple single-cell protein expression measurements. The significant biological and technical variance in cytometry has posed a formidable challenge during the gating process, especially for the initial pre-gate...

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Váldodahkkit: Jiong Chen, Matei Ionita, Yanbo Feng, Yinfeng Lu, Patryk Orzechowski, Sumita Garai, Kenneth Hassinger, Jingxuan Bao, Junhao Wen, Duy Duong-Tran, Joost Wagenaar, Michelle L. McKeague, Mark M. Painter, Divij Mathew, Ajinkya Pattekar, Nuala J. Meyer, E. John Wherry, Allison R. Greenplate, Li Shen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2025-02-01
Ráidu:Nature Communications
Liŋkkat:https://doi.org/10.1038/s41467-025-56622-2
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