Vaccination with a Protective Ipa Protein-Containing Nanoemulsion Differentially Alters the Transcriptomic Profiles of Young and Elderly Mice following <i>Shigella</i> Infection

<i>Shigella</i> spp. are responsible for bacillary dysentery or shigellosis transmitted via the fecal–oral route, causing significant morbidity and mortality, especially among vulnerable populations. There are currently no licensed <i>Shigella</i> vaccines. <i>Shigella</i> spp. use a type III secret...

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Autores principales:	Ti Lu, Murugesan Raju, Debaki R. Howlader, Zackary K. Dietz, Sean K. Whittier, David J. Varisco, Robert K. Ernst, Lyndon M. Coghill, William D. Picking, Wendy L. Picking
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-06-01
Colección:	Vaccines
Materias:	<i>Shigella</i> spp. type III secretion system vaccine aging immunity dual RNA-seq
Acceso en línea:	https://www.mdpi.com/2076-393X/12/6/618
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