Genomic and functional characterization of a blaNDM-1 and tmexCD2-toprJ2 co-producing Klebsiella quasipneumoniae (KL159/ST1929) reveals plasmid-mediated suppression of virulence

ABSTRACT Klebsiella quasipneumoniae has emerged as a multidrug-resistant (MDR) pathogen of growing clinical concern, driven by its capacity to acquire mobile genetic elements encoding carbapenemases and novel resistance determinants. This study aimed to characterize the genomic architecture, resista...

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Hlavní autoři:	Feng Nie, Tianyu Zou, Ruihang Luo, Maosen Liu, Hongyi Lai, Yanghua Xiao, Jingwen Zhang, Yang Liu, Wei Zhang, Ping Li, Tianxin Xiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2026-04-01
Edice:	Microbiology Spectrum
Témata:	Klebsiella quasipneumoniae blaNDM-1 tmexCD2-toprJ2 plasmid curing antimicrobial resistance virulence suppression
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.02401-25
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