A regulatory mechanism involving TBP-1/Tat-Binding Protein 1 and Akt/PKB in the control of cell proliferation.

TBP-1 /Tat-Binding Protein 1 (also named Rpt-5, S6a or PSMC3) is a multifunctional protein, originally identified as a regulator of HIV-1-Tat mediated transcription. It is an AAA-ATPase component of the 19S regulative subunit of the proteasome and, as other members of this protein family, fulfils di...

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Autors principals:	Maria Sepe, Luisa Festa, Fabio Tolino, Luca Bellucci, Luca Sisto, Daniela Alfano, Pia Ragno, Viola Calabrò, Vittorio de Franciscis, Girolama La Mantia, Alessandra Pollice
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2011-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC3186787?pdf=render
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