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The impact of developmental stage, tissue type, and sex on DNA double-strand break repair in Drosophila melanogaster.

Accurate repair of DNA double-strand breaks (DSBs) is essential for the maintenance of genome integrity, as failure to repair DSBs can result in cell death. The cell has evolved two main mechanisms for DSB repair: non-homologous end-joining (NHEJ) and homology-directed repair (HDR), which includes s...

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Hlavní autoři: Elizabeth L Graham, Joel Fernandez, Shagun Gandhi, Iqra Choudhry, Natalia Kellam, Jeannine R LaRocque
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2024-04-01
Edice:PLoS Genetics
On-line přístup:https://doi.org/10.1371/journal.pgen.1011250
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