Macrophage spatiotemporal plasticity in pulmonary diseases: decoding the niche at single-cell resolution

Pulmonary gas exchange and host defense depend on the dynamic coordination of resident and recruited macrophage populations. Historically, macrophage functions have often been interpreted through the classic M1/M2 dichotomy; however, this binary framework does not capture the heterogeneity and conte...

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Hlavní autoři:	Chenchen Lin, Shaohui Huang, Li Yang, Ziqi Wang, Huanhuan Zhou, Quncheng Zhang, Xiaoju Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-06-01
Edice:	Frontiers in Immunology
Témata:	cell–cell communication macrophage heterogeneity metabolic reprogramming pulmonary macrophages single-cell RNA sequencing spatiotemporal plasticity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1855906/full
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