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Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

Cholecystokinin (CCK) is an essential modulator for neuroplasticity in sensory and emotional domains. Here, we investigated the role of CCK in motor learning using a single pellet reaching task in mice. Mice with a knockout of Cck gene (Cck−/−) or blockade of CCK-B receptor (CCKBR) showed defective...

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Main Authors: Hao Li, Jingyu Feng, Mengying Chen, Min Xin, Xi Chen, Wenhao Liu, Liping Wang, Kuan Hong Wang, Jufang He
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications Ltd 2024-05-01
Series:eLife
Subjects:
cholecystokinin
entorhinal cortex
motor cortex
single pellet reaching task
motor skill learning
Online Access:https://elifesciences.org/articles/83897
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