Oral administration of MCT oil reduces anxiety-like behavior and is associated with differences in serum BDNF responses in a rat model of PTSD

Abstract Post-traumatic stress disorder (PTSD) is characterized by neuroinflammatory and neurotrophic dysregulation, and effective interventions remain limited. Medium-chain triglyceride (MCT) oil, a dietary source of ketone bodies, may offer a practical means to elevate circulating β-hydroxybutyrat...

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Autori principali:	Daisuke Yoshioka, Takehiko Yamanashi, Koji Komatsu, Naofumi Kajitani, Chika Ushida, Miyu Matsumi, Moyu Nakamoto, Kaori Adachi, Ryoichi Matsuo, Akihiko Miura, Tsuyoshi Nishiguchi, Masaaki Iwata
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-04-01
Serie:	Scientific Reports
Soggetti:	Post-traumatic stress disorder Medium-chain triglyceride β-hydroxybutyrate Brain-derived neurotrophic factor Anxiety-like behavior
Accesso online:	https://doi.org/10.1038/s41598-026-46116-6
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