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Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking

Targeted positioning of water channel aquaporin-2 (AQP2) strictly regulates body water homeostasis. Trafficking of AQP2 to the apical membrane is critical for the reabsorption of water in renal collecting ducts. Besides the cAMP-mediated effect of vasopressin on AQP2 trafficking to the apical membra...

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Autors principals: Yumi Noda, Sei Sasaki
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2004-01-01
Col·lecció:Journal of Pharmacological Sciences
Accés en línia:http://www.sciencedirect.com/science/article/pii/S1347861319323345
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