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Ubiquitin-specific protease 7 maintains c-Myc stability to support pancreatic cancer glycolysis and tumor growth

Abstract Background The typical pathological feature of pancreatic ductal adenocarcinoma (PDAC) is a significant increase in stromal reaction, leading to a hypoxic and poorly vascularized tumor microenvironment. Tumor cells undergo metabolic reprogramming, such as the Warburg effect, yet the underly...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jichun Gu, Xi Xiao, Caifeng Zou, Yishen Mao, Chen Jin, Deliang Fu, Rongkun Li, Hengchao Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-12-01
Rangatū:Journal of Translational Medicine
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12967-024-05962-6
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