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Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable.

X-chromosome inactivation (XCI) silences one X in female cells to balance sex-differences in X-dosage. A subset of X-linked genes escape XCI, but the extent to which this phenomenon occurs and how it varies across tissues and in a population is as yet unclear. To characterize incidence and variabili...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Antonino Zito, Amy L Roberts, Alessia Visconti, Niccolo' Rossi, Rosa Andres-Ejarque, Stefano Nardone, Julia S El-Sayed Moustafa, Mario Falchi, Kerrin S Small
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2023-02-01
Cyfres:PLoS Genetics
Mynediad Ar-lein:https://doi.org/10.1371/journal.pgen.1010556
Tagiau: Ychwanegu Tag
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