Microbiota modulate immune cell populations and drive dynamic structural changes in gut-associated lymphoid tissue

Inbred mouse strains provide phenotypic homogeneity between individual mice. However, stochastic morphogenetic events combined with epigenetic changes due to exposure to environmental factors and ontogenic experience result in variability among mice with virtually identical genotypes, reducing the r...

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Bibliografische Detailangaben

Hauptverfasser:	Jan Pačes, Nikola Malinská, Liliana Tušková, Karolina Knížková, Valéria Grobárová, Zdeněk Zadražil, Tomáš Hudcovic, Anna Michl, Dagmar Šrůtková, Martin Schwarzer, Marianne Boes, Jan Černý
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2025-12-01
Schriftenreihe:	Gut Microbes
Schlagworte:	Phenotypic plasticity Microbiota-induced immunity Gut-associated lymphoid tissue (GALT) MHCII-EGFP knock-in mice Germ-free and gnotobiotic models Lymphoid tissue morphogenesis
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/19490976.2025.2543908
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