QbD-Based Development of Self-Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution
Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self-nanoemulsifying drug delivery system (SNEDDS) for the codelivery of...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2025-01-01
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| Serier: | Journal of Nanotechnology |
| Online adgang: | http://dx.doi.org/10.1155/jnt/8346300 |
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