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Synthesis, antioxidant and antimicrobial activities, molecular docking study of new pyrimidine derivatives

Abstract Organic compounds, especially heterocyclic compounds, are known for their significant bioactivity, in this work, novel pyrimidine derivatives 3–11 were synthesized from the reaction of chalcon compound 1 with hydrogen peroxide to give oxiran compound 2 which reacted with thiourea producing...

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Bibliographic Details
Main Authors: Hemat S. Khalaf, Ahmed A. El-Rashedy, Amina A. Abd El-Gwaad, Ahmed A. Fayed
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2026-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-026-45654-3
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