Detection of the Plasmodium falciparum Kelch-13 gene P553L mutation in sporozoites isolated from mosquito salivary glands in South-Central Vietnam

Abstract Background Plasmodium falciparum has developed resistance against artemisinin in Southeast Asia. Mutations in the P. falciparum Kelch-13 (Pfk13) gene are associated with artemisinin resistance in vitro and in vivo. We investigated the prevalence of mutations in PfK13 from sporozoite-stage p...

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Detalhes bibliográficos

Principais autores:	Yoshimasa Maeno, Nguyen Tuyen Quang, Richard Culleton, Satoru Kawai, Gaku Masuda, Kaoru Hori, Shusuke Nakazawa, Ron P. Marchand
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-06-01
coleção:	Parasites & Vectors
Assuntos:	Plasmodium falciparum Anopheles dirus Sporozoite Artemisinin resistance K13-propeller gene Vietnam
Acesso em linha:	http://link.springer.com/article/10.1186/s13071-017-2247-9
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