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Multiple phosphatidylinositol 3-kinases regulate vaccinia virus morphogenesis.

Poxvirus morphogenesis is a complex process that involves the successive wrapping of the virus in host cell membranes. We screened by plaque assay a focused library of kinase inhibitors for those that caused a reduction in viral growth and identified several compounds that selectively inhibit phosph...

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Autores principales: Shannon McNulty, William Bornmann, Jill Schriewer, Chas Werner, Scott K Smith, Victoria A Olson, Inger K Damon, R Mark Buller, John Heuser, Daniel Kalman
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2010-05-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC2878334?pdf=render
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