Combined Delivery of miR-15/16 through Humanized Ferritin Nanocages for the Treatment of Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is a widespread type of leukemia that predominantly targets B lymphocytes, undermining the balance between cell proliferation and apoptosis. In healthy B cells, miR-15/16, a tandem of microRNAs, functions as a tumor suppressor, curbing the expression of the antiapo...

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Autori principali:	Francesca Romana Liberati, Sara Di Russo, Lorenzo Barolo, Giovanna Peruzzi, Maria Vittoria Farina, Sharon Spizzichino, Federica Di Fonzo, Deborah Quaglio, Luca Pisano, Bruno Botta, Alessandra Giorgi, Alberto Boffi, Francesca Cutruzzolà, Alessio Paone, Paola Baiocco
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-03-01
Serie:	Pharmaceutics
Soggetti:	ferritin nanocages Bcl-2 miR-15a miR-16-1 delivery leukemia self-assembly
Accesso online:	https://www.mdpi.com/1999-4923/16/3/402
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