Early-Life Stress Does Not Aggravate Spatial Memory or the Process of Hippocampal Neurogenesis in Adult and Middle-Aged APP/PS1 Mice

Life-time experiences are thought to influence the risk to develop the neurodegenerative disorder Alzheimer’s disease (AD). In particular, early-life stress (ES) may modulate the onset and progression of AD. There is recent evidence by our group and others that AD-related neuropathological progressi...

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Principais autores:	Lianne Hoeijmakers, Anna Amelianchik, Fleur Verhaag, Janssen Kotah, Paul J. Lucassen, A. Korosi
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2018-03-01
סדרה:	Frontiers in Aging Neuroscience
נושאים:	early-life adversity neuroplasticity Alzheimer’s disease neurogenesis Morris water maze hippocampus
גישה מקוונת:	http://journal.frontiersin.org/article/10.3389/fnagi.2018.00061/full
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