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Melt Amorphisation of Orlistat with Mesoporous Silica Using a Supercritical Carbon Dioxide: Effects of Pressure, Temperature, and Drug Loading Ratio and Comparison with Other Conventional Amorphisation Methods

The aim of this work was to develop an amorphous orlistat-loaded mesoporus silica formulation using the melt-amorphisation by supercritical fluid (MA-SCF) and to investigate the effects of pressure and temperature on the pharmaceutical properties of the developed formulation. In addition, the effect...

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Váldodahkkit: Heejun Park, Kwang-Ho Cha, Seung Hyeon Hong, Sharif Md Abuzar, Eun-Sol Ha, Jeong-Soo Kim, Min-Soo Kim, Sung-Joo Hwang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2020-04-01
Ráidu:Pharmaceutics
Fáttát:
Liŋkkat:https://www.mdpi.com/1999-4923/12/4/377
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