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Two remarkable serine/leucine polymorphisms in Helicobacter pylori: functional importance for serine protease HtrA and adhesin BabA

Abstract Single nucleotide polymorphisms (SNPs) account for significant genomic variability in microbes, including the highly diverse gastric pathogen Helicobacter pylori. However, data on the effects of specific SNPs in pathogen-host interactions are scarce. Recent functional studies unravelled how...

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Principais autores: Steffen Backert, Nicole Tegtmeyer, Anselm H. C. Horn, Heinrich Sticht, Bodo Linz
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-05-01
Serier:Cell Communication and Signaling
Fag:
BabA
HtrA
Evolution
Adaptation
SNP
Online adgang:https://doi.org/10.1186/s12964-024-01635-5
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