Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E. coli NarL and previous studies have indicated that it is composed...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	David Kim, John Tracey, Manuel Becerra Flores, Kanita Chaudhry, Rafae Nasim, Abraham Correa-Medina, Leslie Knipling, Qing Chen, Scott Stibitz, Lisa M.M. Jenkins, Kyung Moon, Tim Cardozo, Deborah M. Hinton
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Association for the Advancement of Science (AAAS) 2022-01-01
Schriftenreihe:	Computational and Structural Biotechnology Journal
Schlagworte:	Bordetella pertussis Response regulator BvgA Two-component system FeBABE
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2001037022004895
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