AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

AMPK integrates information about a cell’s energy status to inform decisions about cellular processes, including autophagy. Here the authors identify cyclin Y as an AMPK substrate, which phosphorylates cyclin Y and promotes its interaction with CDK16 to stimulate autophagy.

書誌詳細

主要な著者:	Marc Dohmen, Sarah Krieg, Georgios Agalaridis, Xiaoqing Zhu, Saifeldin N. Shehata, Elisabeth Pfeiffenberger, Jan Amelang, Mareike Bütepage, Elena Buerova, Carolina M. Pfaff, Dipanjan Chanda, Stephan Geley, Christian Preisinger, Kei Sakamoto, Bernhard Lüscher, Dietbert Neumann, Jörg Vervoorts
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2020-02-01
シリーズ:	Nature Communications
オンライン･アクセス:	https://doi.org/10.1038/s41467-020-14812-0
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!