DeepBindRG: a deep learning based method for estimating effective protein–ligand affinity

Proteins interact with small molecules to modulate several important cellular functions. Many acute diseases were cured by small molecule binding in the active site of protein either by inhibition or activation. Currently, there are several docking programs to estimate the binding position and the b...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Haiping Zhang, Linbu Liao, Konda Mani Saravanan, Peng Yin, Yanjie Wei
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	PeerJ Inc. 2019-07-01
Цуврал:	PeerJ
Нөхцлүүд:	Protein–ligand binding affinity ResNet Deep neural network Native-like protein–ligand complex Drug design
Онлайн хандалт:	https://peerj.com/articles/7362.pdf
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!