Discovery of potent cross-neutralizing antibodies against Marburg and Ravn viruses with therapeutic potential

Abstract Marburg virus (MARV) and Ravn virus (RAVV) are highly pathogenic filoviruses that cause Marburg virus disease (MVD), for which no approved treatment currently exists. In this study, we describe a panel of 10 novel mouse-derived monoclonal antibodies (mAbs), all exhibiting neutralizing activ...

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Autors principals:	Takeshi Saito, Hiroko Miyamoto, Manabu Igarashi, Asuka Nanbo, Risa Hayashi, Ruchi Paroha, Gavriella Siman-Tov, Kirsten Littlefield, Akina Mori-Kajihara, Christine Click, Wakako Furuyama, Slobodan Paessler, Junki Maruyama, Ayato Takada
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	npj Viruses
Accés en línia:	https://doi.org/10.1038/s44298-025-00168-z
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