An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors

Abstract Background Viral vectors are attractive gene delivery vehicles because of their broad tropism, high transduction efficiency, and durable expression. With no risk of integration into the host genome, the vectors developed from RNA viruses such as Sendai virus (SeV) are especially promising....

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Hlavní autoři:	Takumi Kishimoto, Ken Nishimura, Kana Morishita, Aya Fukuda, Yusaku Miyamae, Yutaro Kumagai, Kimio Sumaru, Mahito Nakanishi, Koji Hisatake, Masayuki Sano
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-01-01
Edice:	Journal of Biological Engineering
Témata:	Sendai virus Csy4 Ligand Gene regulation ES cells Neural differentiation
On-line přístup:	https://doi.org/10.1186/s13036-024-00404-9
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