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Functional Characterization of Dense Granule Proteins in Toxoplasma gondii RH Strain Using CRISPR-Cas9 System

Infection with the apicomplexan protozoan parasite Toxoplasma gondii is an ongoing public health problem. The parasite's ability to invade and replicate within the host cell is dependent on many effectors, such as dense granule proteins (GRAs) released from the specialized organelle dense granules,...

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Hlavní autoři: Meng-Jie Bai, Jin-Lei Wang, Hany M. Elsheikha, Qin-Li Liang, Kai Chen, Lan-Bi Nie, Xing-Quan Zhu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-08-01
Edice:Frontiers in Cellular and Infection Microbiology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fcimb.2018.00300/full
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