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In Silico and In Vitro Screening of Serine Racemase Agonist and In Vivo Efficacy on Alzheimer’s Disease <i>Drosophila melanogaster</i>

The NMDA receptor hypofunction has been implicated in schizophrenia, memory impairment, and Alzheimer’s disease. Modulating the abundance of D-serine, a co-agonist of the NMDA receptor, is a strategy to treat symptoms of the NMDA receptor hypofunction. In contrast to D-amino acid oxidase (DAAO) inhi...

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Detaylı Bibliyografya
Asıl Yazarlar: Chih-Hao Lu, Hao-Teng Chang, Lee-Fen Hsu, Ming-Hsueh Lee, Jack Cheng, Dong Chuan Wu, Wei-Yong Lin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2023-02-01
Seri Bilgileri:Pharmaceuticals
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Online Erişim:https://www.mdpi.com/1424-8247/16/2/280
Etiketler: Etiketle
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