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Strategies for Accelerating the Development of Catalytic Enantioselective Reactions

The development of enantioselective catalytic processes for the manufacture of chiral intermediates is a very complex endeavor and can be very time consuming and expensive. In this contribution the major issues which might lead to long development times will be discussed and strategies to...

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Principais autores: Hans-Ulrich Blaser, Garrett Hoge, Matthias Lotz, Ulrike Nettekoven, Anita Schnyder, Felix Spindler
Formato: Artigo
Idioma:Alemão
Publicado em: Swiss Chemical Society 2008-06-01
coleção:CHIMIA
Assuntos:
Asymmetric hydrogenation
Chiral diphosphines
Enantioselective hydrogenation
Process development
Solvias ligands
Technical process
Acesso em linha:https://www.chimia.ch/chimia/article/view/4517
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