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G12R mutation in Cx26 downregulates the expression levels of TLR2 and its downstream inflammatory factors in keratinocytes

Objective To investigate the effect of G12R mutation in Cx26 on the expression of TLR2 and its downstream inflammatory factors in human keratinocytes. Methods Human keratinocytes (HaCaT) without (WT-Cx26) or with G12R-mutation (G12R-Cx26) were co-cultured with Trichophyton rubrum. Expression levels...

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Principais autores: Zhaoying LIU, Yankun LU, Han MA
Format: Artigo
Sprog:Chinês
Udgivet: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2023-02-01
Serier:Pifu-xingbing zhenliaoxue zazhi
Fag:
keratitis, ichthyosis and deafness syndrome
keratinocytes
richophyton rubrum
tlr2
cx26
Online adgang:http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.01.009
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