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Optimized Polyethylene Glycolylated Polymer–Lipid Hybrid Nanoparticles as a Potential Breast Cancer Treatment

Purpose: The aim of this work is to optimize a polyethylene glycolated (PEGylated) polymer–lipid hybrid nanoparticulate system for the delivery of anastrozole (ANS) to enhance its biopharmaceutical attributes and overall efficacy. Methods: ANS loaded PEGylated polymer–lipid hybrid nanoparticles (PLN...

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Principais autores: Salam Massadeh, Mustafa E Omer, Asmaa Alterawi, Rizwan Ali, Fayez H Alanazi, Fares Almutairi, Wejdan Almotairi, Faris F Alobaidi, Khulud Alhelal, Mansour S Almutairi, Abdulaziz Almalik, Aiman A. Obaidat, Manal Alaamery, Alaa Eldeen Yassin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-07-01
coleção:Pharmaceutics
Assuntos:
anastrozole
poly-caprolactone
PEGylated-polymeric nanoparticles
DSC
Acesso em linha:https://www.mdpi.com/1999-4923/12/7/666
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