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CircCCDC66 promotes the progression and EMT of renal cell carcinoma via the miR-1278/HOXA13 axis

Abstract Background Renal cell carcinoma (RCC) is a common lethal malignancy of the urinary system with a complex pathogenesis. Among its subtypes, clear cell renal cell carcinoma (ccRCC) represents the predominant pathological type. Circular RNAs (circRNAs), a class of covalently closed RNA molecul...

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Autores principales: Zheng Peng, Qing Wang, Kunyuan Huang, Xiaolong Chen, Guanyun Deng, Jinyu Luo, Jianguo Zhu, Kehua Jiang
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2026-01-01
Colección:Journal of Translational Medicine
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Acceso en línea:https://doi.org/10.1186/s12967-025-07573-1
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