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Arsenic trioxide and all-trans retinoic acid (ATRA) treatment for acute promyelocytic leukemia in all risk groups: study protocol for a randomized controlled trial

Abstract Background The treatment of acute promyelocytic leukemia (APL) has been revolutionized in the past two decades by the advent of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO). It suggests that non-high-risk APL patients can be cured without chemotherapy. However, ATRA plus chemot...

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Principais autores: Xinxin Zhang, Huiyun Zhang, Limei Chen, Mengchang Wang, Jieying Xi, Xin Liu, Ming Xie, Dengzhe Li, Ekamjyot Singh Gulati, Sha Gong, Huaiyu Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-09-01
Serier:Trials
Fag:
Acute promyelocytic leukemia
Arsenic trioxide
All-trans retinoic acid
Hydroxyurea
Mannitol
Online adgang:http://link.springer.com/article/10.1186/s13063-018-2812-3
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