Decoding benign prostatic hyperplasia at single-cell resolution: heterogeneity, inflammation, and beyond androgen-driven pathogenesis

Benign prostatic hyperplasia (BPH) represents a highly prevalent age-related disorder, traditionally managed through androgen-driven pathways. However, the limited efficacy of conventional hormonal therapies in a substantial subset of patients necessitates the investigation of alternative pathogenic...

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Autors principals:	Yihao Liao, Siyuan Jiang, Haohan Wang, Sihai Zhou, Honggang Yuan, Xuanxuan Zou, Xiaobo Chen
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	benign prostatic hyperplasia cellular senescence immune microenvironment precision medicine single-cell RNA sequencing
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1881717/full
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