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Apigenin and its octoic acid diester attenuated glycidol-induced autophagic-dependent apoptosis via inhibiting the ERK/JNK/p38 signaling pathways in human umbilical vein endothelial cells (HUVECs)

Glycidol is a well-known food contaminant mainly formed in refined edible oils and various thermally processed foods. Here, we studied the toxicity effects and related mechanism of glycidol on Human umbilical vein endothelial cells (HUVECs). Glycidol was found to induce Gap period 2 (G2)/Mitosis (M)...

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Principais autores: Yue Zhao, Qingqing Jiang, Limin Guo, Daming Fan, Mingfu Wang, Yueliang Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-01-01
Serier:Current Research in Food Science
Fag:
Glycidol
Autophagy
Apoptosis
Apigenin
Mitogen-activated protein kinase (MAPK)
MAPK signaling Pathway
Online adgang:http://www.sciencedirect.com/science/article/pii/S2665927123000151
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