Cancer cell – Fibroblast crosstalk via HB-EGF, EGFR, and MAPK signaling promotes the expression of macrophage chemo-attractants in squamous cell carcinoma

Summary: Interactions between cells in the tumor microenvironment (TME) shape cancer progression and patient prognosis. To gain insights into how the TME influences cancer outcomes, we derive gene expression signatures indicative of signaling between stromal fibroblasts and cancer cells, and demonst...

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Bibliografski detalji

Glavni autori:	Giovanni Giangreco, Antonio Rullan, Yutaka Naito, Dhruva Biswas, Yun-Hsin Liu, Steven Hooper, Pablo Nenclares, Shreerang Bhide, Maggie Chon U Cheang, Probir Chakravarty, Eishu Hirata, Charles Swanton, Alan Melcher, Kevin Harrington, Erik Sahai
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-09-01
Serija:	iScience
Teme:	Microenvironment Cancer Transcriptomics
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2589004224018601
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