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Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production [version 2; peer review: 2 approved]

Background: Andrographolide (Andro) is a diterpenoid component of the plant Andrographis paniculata that is known for its anti-tumor activity against a variety of cancer cells.   Methods: We studied the effects of Andro on the viability of the human leukemia monocytic cell line THP-1 and the human m...

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Principais autores: Tamae Ohye, Hiromu Takematsu, Johannes M. Dijkstra, Itsuro Katsuda, Hidehiko Akiyama, Taei Matsui, Atsushi Ogasawara, Yuki Higashimoto, Seiji Imamura, Hiroki Doi
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Ltd 2021-12-01
Serier:F1000Research
Fag:
Andrographis paniculata
andrographolide
apoptosis
reactive oxygen species
monocytic leukemia cells
multiple myeloma cells
eng
Online adgang:https://f1000research.com/articles/10-542/v2
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