Natural mutations in key NLS amino acids regulate nucleoplasmic shuttling and replication efficiency in PRRSV

Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is a mutant strain of the classic porcine reproductive and respiratory syndrome virus (PRRSV) characterized by high morbidity and mortality rates. Epidemiological analysis revealed a natural mutation and stable inherita...

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Главные авторы:	Xianchang Zhu, Yang Xia, Qian Lei, Yu Gan, Shenghai Jiang, Lian Huang, Qihu Wen, Wei Fu, Bo Zhang, Yi Zhang, Shanshan Xie, Jida Li
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-07-01
Серии:	Frontiers in Microbiology
Предметы:	PRRSV nucleocapsid protein NLS NTR nuclear-mass shuttle
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1587634/full
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